[U.S. Stock Market Pre-Market: Crypto Concept Stocks Generally Decline, MSTR Down 4.48%] On November 21, U.S. stock market pre-market crypto concept stocks continued their downward trend, with Strategy (MSTR) down 4.48%, Circle (CRCL) down 1.45%, Coinbase (COIN) down 2.54%, MARA Holdings (MARA) down 3.03%, Riot Platforms (RIOT) down 4.93%, Bitmine Immersion (BMNR) down 3.5%, and SharpLink Gaming (SBET) down 3.76%.