[BIO Launches on BNB Chain and Releases Strategic Expansion Roadmap] On December 4, Bio Protocol announced that BIO has launched on BNB Chain, and users can trade BIO on PancakeSwap on the BNB Chain. In the coming weeks, more DeSci tokens will be launched, laying the foundation for the development of Bio's Launchpad and x402-supported BioAgents on BNB Chain. Bio plans to provide full-stack solutions for DeSci builders and the research community to accelerate scientific research by 100 times. The roadmap includes: DeSci Bridge (completed), BIO deposits and withdrawals on Binance platform via BNB Chain, x402 BNB for BioAgent payments, cross-chain DeSci projects, DeSci staking, Bio Launchpad on BNB Chain mainnet, and Ignition sales.

[Aave Passes Proposal to Remove USDS Collateral Eligibility and Increase Reserve Factor to 25%] The Aave community has passed a proposal to remove USDS collateral eligibility (reducing LTV to 0), exclude it from e-Mode, and increase the reserve factor from 10% to 25%. The proposal is currently awaiting final execution via AIP. This adjustment is due to declining USDS yield contributions, low collateral utilization, and potential risks in its issuance mechanism. MakerDAO founder Rune responded, stating that the proposal misunderstands the borrowing methods of Stars like Spark and Grove from Sky. He also mentioned that if Sky improves transparency and scalability in the future through DataHub, Grove, and Sentinel Network, USDS could still return to Aave's list of collateral assets.

[Columbus Circle Capital Corp I Shareholders Approve Merger with ProCap BTC] Columbus Circle Capital Corp I (NASDAQ: BRR) shareholders approved the business merger with Bitcoin financial services company ProCap BTC on December 3, 2025. The transaction is expected to be completed on December 5, after which the merged company will be renamed ProCap Financial, Inc. and will continue trading on the Nasdaq Global Market under the ticker symbol 'BRR.' ProCap BTC has raised over $750 million from investors in the traditional finance and Bitcoin industries.

Monitoring shows that a giant whale has deposited $1.18 million USDC into Hypeer Liquid and opened a long position in HYPE with 5-fold leverage, while also placing orders to increase positions. In another wallet, the whale holds a long position in HYPE with 6 times leverage, currently with a floating profit of $850000. （Onchain Lens）

[Former Coinbase Product Director Nemil Dalal Joins Y Combinator as Visiting Partner] Former Coinbase Product Director Nemil Dalal will join Y Combinator as a Visiting Partner, focusing on the crypto sector. Nemil Dalal stated that Y Combinator had a profound impact on him in 2012, helping him gain experience and driving the development of products such as USDC, Coinbase Developer Platform, and x402. Nemil Dalal worked at Coinbase for 7 years, advancing the development of USDC, DeFi, and developer tools.